While investigating a death that took place at a reunion at Quantico, the NCIS team uncover a bomb plot which soon leads them to a long-running theft ring while Torres and Quinn adjust to life as members of Gibbs's team which also includes new sitting arrangements and the bullpen's structure also changing in the process.
- Torres and Quinn begin their tenure as the new members of the main NCIS Major Case Response Team.
In an episode fashioned after "The Breakfast Club", Vice Principal Victor Castor is played by John Kapelos; aka Carl the Janitor at Shermer High School, home of The Breakfast Club.
|Leroy Jethro Gibbs||Mark Harmon||Special Agent in charge of the NCIS Major Case Response Team.|
|Abigail Sciuto||Pauley Perrette||Chief Forensic Specialist for the NCIS Major Case Response Team.|
|Timothy McGee||Sean Murray (actor)||Senior Special Agent and second-in command of the NCIS Major Case Response Team.|
|Nicholas Torres||Wilmer Valderrama||Special Agent for the NCIS Major Case Response Team.|
|Alexandra Quinn||Jennifer Esposito||Special Agent for the NCIS Major Case Response Team.|
|Eleanor Bishop||Emily Wickersham||Probationary Agent for the NCIS Major Case Response Team.|
|James Palmer||Brian Dietzen||Assistant Medical Examiner for the NCIS Major Case Response Team.|
|Leon Vance||Rocky Carroll||Director of NCIS. Despite being credited, Carroll does not appear in this episode.|
|Donald Mallard||David McCallum||Chief Medical Examiner for the NCIS Major Case Response Team.|
|Helen Frimkes||Vernee Watson-Johnson||The killer.|
|Vic Castor||John Kapelos||Vice Principal.|
|Neal Sherwood||Braden Lynch||The Brain|
|Adam Cooper||Joshua LeBar||The Athlete|
|Angela Russell||Devin Sidell||The Basket Case|
|Katrina Cooper||Amy Gumenick||The Princess|
|Jim Bruno||Mike Falkow||The Criminal (and the victim).|
|Milo Torbush||Conner Marx||AKA "Buddy".|