Former FBI Agent Tobias Fornell who's now a Private Investigator pleads with Gibbs to do whatever is necessary to take down drug dealers and suppliers in the area after his daughter, Emily Fornell, is hospitalized from an opiate overdose while Gibbs is haunted by the personal aspects of the case and also his own history with vigilante justice.
- Emily Fornell was revealed to have become a drug addict largely because of Tobias's overprotective actions to his daughter.
- Ziva David is revealed to be alive and shows up to Gibbs' basement to inform him his life is in danger.
- It's revealed that Kasie is aware of Torres's feelings towards Bishop.
- Originally, it was to be titled "Alternate Twilight".
- Cote de Pablo who plays Ziva David made her return since season eleven episode "Past, Present, and Future".
|Leroy Jethro Gibbs||Mark Harmon||Special Agent in charge of the NCIS Major Case Response Team.|
|Timothy McGee||Sean Murray||Senior Special Agent and second-in command of the NCIS Major Case Response Team.|
|Eleanor Bishop||Emily Wickersham||Special Agent for the NCIS Major Case Response Team.|
|Nicholas Torres||Wilmer Valderrama||Special Agent for the NCIS Major Case Response Team.|
|Jacqueline Sloane||Maria Bello||NCIS Forensic Psychologist.|
|James Palmer||Brian Dietzen||Chief Medical Examiner for the Major Case Response Team.|
|Kasie Hines||Diona Reasonover||NCIS Forensic Specialist; Abby's replacement.|
|Leon Vance||Rocky Carroll||Director of NCIS|
|Donald Mallard||David McCallum||NCIS Historian|
|Tobias Fornell||Joe Spano||Former FBI Agent|
|Emily Fornell||Juliette Angelo||Fornell's daughter|
|Diane Sterling||Melinda McGraw||Fornell and Gibbs' deceased wife|
|Ziva David||Cote de Pablo||Former NCIS Agent|
|Spencer Cox||AJ Achinger|
|Pharmacist||Robert Clendenin||A pharmacist.|
|Vargas (Daughters)||Yorke G. Fryer||A Doctor and surgeon.|
|Joseph Taylor||Christopher Allen||An overdose victim.|
|Local LEO||Christopher Amitrano|
|Paramedic (Daughters)||Michelle Lukiman|
|Ralph Young||Jd Mendonca||Uncredited role.|
|Technician (Daughters)||Bruce M. Stockert||Uncredited role.|